Bone Abstracts

Introduction: Vitamin D is known to be important for bone health. Still, the significance of serum 25-hydroxy vitamin D concentrations (s-25OHD) for hip fracture risk of the elderly is uncertain. Discordant findings may in part be explained by difficulties of RCTs or large cohort studies to reach both the frail and the healthy elderly. The objectives of this study were to determine the risk of hip fractures of the elderly related to s-25OHD, including both the frail and the he...

Previous studies found a negative correlation between vertebral bone marrow fat (MF) and bone density (BMD). Proposed mechanisms for this include i) a shift in stem cell lineage allocation from osteoblasts towards adipocytes, and ii) an increase in osteoclast-promoting cytokines with greater MF. However, little is known about the relationship between MF and bone markers. To assess these relationships in older adults, we used data from the AGES-Reykjavik cohort. MF was measured...